How Does IV NAD Work?

Our cells continuously produce energy making it possible for us to think, move, play and make sense of the world around us. In a process called “cellular respiration” adenosine triphosphate (ATP) molecules are produced through glucose and oxygen. NADH is crucial in this ATP production process. In this process NAD+ picks up an electron from glucose at which it becomes NADH (By using intravenous NADH instead of NAD+ we short cut this process) und ultimately carries it like a cargo transport to the mitochondria – the factory of the cell – to produce ATP – the energy currency of life. Supporting this process by administering IV NADH may benefit patients in the following areas:

• Mental clarity
• Alertness
• Concentration
• Improved memory
• Improving athletic performance
• Eliminate free radicals
• Reduce brain fog

Without going too much into cellular science and chemistry, to summarize: NADH is involved in the following complex metabolic processes: Glycolysis, oxidation of pyruvate to acetyl CoA, fermentation, and the citric acid cycle.

This multitalented cofactor may support the following beneficial functions:

• NADH is an antioxidant boosting the production of Nitric Oxide that can eliminate free radicals and protect your brain cells. It also relaxes blood vessels in your brain increasing cerebral blood flow.
• NADH is able to repair cell and DNA damage and stimulates your immune system
• NADH provides electrons for ATP production which fuels mitochondria in brain cells thus improving cognitive energy.
• NADH has shown to stimulate the production of neurotransmitters such as dopamine, norepinephrine and serotonin. The increase of these neurotransmitters can improve memory, learning, cognition, recall and mood.

Who Can Benefit from IV NAD Therapy?

The patients with the following conditions may benefit from IV NAD Therapy:

• Parkinson’s disease
• Opposing alcohol’s effects on the liver
• Reducing signs of aging
• Protecting against the side effects of an
  AIDS drug called zidovudine (AZT).

Why is NAD used in Addiction treatment?

NADH has shown to stimulate the production of neurotransmitters such as dopamine, norepinephrine and serotonin. The increase of these neurotransmitters can improve memory, learning, cognition, recall and mood. Alcohol or drug abuse can cause Neurotransmitter depletion and neurotransmitter receptor damage. NADH may assist in repairing the damage and help addiction patients in their recovery and assisting the body to balance the neurotransmitters needed to overcome withdrawal.

NAD+ may be beneficial for patients with impaired liver function due to excess alcohol consumption. Excess alcohol consumption can have a negative effect on the NAD+/NADH ratio. Liver cell enzymes use the oxidizing effect of the NAD+ to NADH conversion process to break down ethanol from alcoholic drinks into acetate – a less toxic compound.

Why do you use NADH instead of NAD or NAD+?

Scientist agree that a balance between NAD+ and NADH is important for cell health and it is impossible to villainize or champion one over the other. NADH is the reduced form of NAD+ further along the chain already charged with a hydrogen molecule. This alleviates the body of the work to convert NAD+ into NADH first. NADH is the mitochondria friendly form of NAD+ which allows the cell to produce ATP without prior necessary processes. That being said the conversion can happen both ways and both substances have their place in therapy depending on what processes we want to support. Infusio’s IV therapies focus on neurological repair, brain health and chronic fatigue for which NADH is better suited cofactor.

Can you boost your NADH levels with food?

The body needs niacin to produce NADH. Niacin can be found in meat, poultry, oily fish, peanuts, avocados, asparagus, broccoli, potatoes, and liver. This means to avoid overeating on these foods in order to boos NADH, the only way to boost levels is by supplementing the body with additional NADH. The most superior and efficient way of supplementation is IV therapy.

General Resources

NAD Therapy (Wikipedia)

Scientific Articles

• Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome
• Effects of nicotinamide adenine dinucleotide hydride on physical and mental performance.
• Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.
• Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue syndrome?
• Kynurenine Pathway Pathologies: do Nicotinamide and Other Pathway Co-Factors have a Therapeutic Role in Reduction of Symptom Severity, Including Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM).